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Sulfasalazine acts as a competitive inhibitor of SLC7A11 by interacting with the backbone of TM1a and R396 as well as Y240, Y244, and Y444 of SLC7A11 [203]

These recommendations reflect strong data for A1C reduction, hypoglycemia mitigation, and time-in-range improvements

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More so, it produces bile acid which is released to help to break down fats in the small intestine and allows the gallbladder to secrete bile