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Dietary iron restriction alleviates renal tubulointerstitial injury induced by protein overload in mice

Moreover, oxidative stress upregulates adhesion molecules like intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on orbital fibroblasts and endothelial cells, facilitating immune cell recruitment and adhesion to inflamed orbital tissue (88, 89)

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We found that ethanol administration caused a 2.3-fold increase in the 3-NT protein level, which paralleled a significant induction of 3-NT protein staining that was, again, distinctly colocalized with the neuronal marker NeuN, suggesting that 3-nitrotyrosine protein adducts were formed because of iNOS induction (Figs