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Preventing Depletion One of the most important roles of milk thistle is defensive

TLK199 and TLK117 Ezatiostat hydrochloride (TLK199), a glutathione derivate and inhibitor of GSTP1, is developed for the treatment of myelodysplastic syndromes (MDS) (Figure 8A) [172]

1999;276:G1G6

Berstad A, Weberg R, Larsen IF, Hoel B, Hauer-Jensen M

Although high ROS levels cause cellular damage and dysfunction, a low basal level of ROS is considered advantageous for maintaining cellular proliferation, differentiation, and survival [31, 32]
