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No significant between-group differences were observed

A 2015 paper in Nature Scientific Reports identified that gut microbiota actually convert berberine into dihydroberberine (DHB) in the intestinal wall, and it's the DHB that gets absorbed and then converts back to berberine in the bloodstream

[DOI] [PubMed] [Google Scholar] Seino T., Sato H., Yamamoto A., Nemoto A., Torimura M., Tao H

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