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Furthermore, membrane permeant inhibitor of MLCK (PIK), which reverses MLC phosphorylation, mitigates tumor necrosis factor alpha (TNF)-induced decreases in transepithelial resistance in cell culture and protects against gut damage in a model of binge ethanol exposure and burn injury [55, 56]

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Hormone replacement or modulation (thyroid, prolactin, insulin sensitizers) addresses endocrine-driven infertility

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