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On top of demonstrating T-MSCs-Exos potential, the study also highlighted that exosomal miRNAs, such as miR-100-5p, may play an important role in the regulation of oxidative stress and neuron protection in PD
This analysis showed that the Phenylalanine metabolism and the Biosynthesis of unsaturated fatty acids were enriched in the severe disease and deceased groups

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145 Telaglenastat, a glutaminase inhibitor, was also evaluated in combination with everolimus (TelaE) in a phase I trial of advanced/metastatic renal cell carcinoma (mRCC), and TelaE therapy was well tolerated in patients previously treated with TKIs and checkpoint inhibitors (NCT03163667)
