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Similarly, in patients with carnitine-acylcarnitine translocase deficiency (CACTD), the carnitine shuttle system does not function and LCFAs cannot be transported inside the mitochondrial matrix for beta oxidation

(PubMed) Zimmermann MB, Galetti V

Acylcarnitines that accumulate through disordered carnitine metabolism directly inhibit the surface activity of pulmonary surfactants and are considered risk factors for increased lung injury due to a second hit, such as respiratory tract infection, sepsis, or inhalation of toxins, in patients with dysregulated FAO [304, 305]

L-tyrosine is a naturally occurring amino acid that is a precursor (building block) for dopamine , epinephrine , and norepinephrine

doi: 10.1016/j.neures.2009.06.008