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Promising approaches to circumvent the bloodbrain barrier: progress, pitfalls and clinical prospects in brain cancer

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Matrix Metalloproteinase Modulation GHK-Cu potently modulates the activity of matrix metalloproteinases (MMPs), a family of enzymes that degrade extracellular matrix components - while this might seem counterproductive for regeneration, controlled MMP activity is actually essential for proper tissue remodeling, removing damaged matrix to allow replacement with newly synthesized healthy matrix

JAMA 317 , 25152523 (2017)
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