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Although carnitine has been well tolerated, future studies are needed to evaluate the efficacy of prophylactic carnitine supplementation for the prevention of hepatotoxicity. 12 Some experimental and clinical data suggest that early intravenous supplementation with l-carnitine could improve survival in severe VPA-induced hepatotoxicity

They can provide additional support when natural production is insufficient or require an extra boost during increased demand or compromised health

However, many studies show that adequate vitamin levels are essential for optimal health

50 Though these findings are not directly associated with IC pathogenicity, the data suggest that ICs could limit the effectiveness of therapeutic antibodies in humans

Consequently, medicines and dietary supplements comprising sulfur-containing biomolecules are widely distributed to aid in disease management and improve quality of life
