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This is especially true when mycotoxins stimulate mast cell and microglial activation, two immune pathways that can profoundly impact brain function 25

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Adesida A, Edwards LG, Thornalley PJ
When the two amino acid changes Ala34Glu and Arg37Trp are introduced into human GR, the resulting mutant enzyme (GRTR) prefers trypanothione 700-fold over its original substrate, effectively converting a GR into a TR [Bradley, M., Bcheler, U

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