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An imbalance in favor of antioxidants can lead to so-called antioxidative stress, which may also have harmful effects, particularly when synthetic antioxidants are consumed in excessive amounts [165]

Elevated levels of platelet microparticles are associated with disease activity in rheumatoid arthritis

Typical oral doses range from 100500 mg daily in divided doses, though tolerance and liver safety must be monitored closely, especially in patients with compromised hepatic function

The link between infection, excess oxidative stress, and inflammation Current studies in the literature report excess vitamin D deficiency [[3], [4], [5], [6], [7], [8], [9], [10], [11], [12]] and elevated levels of proinflammatory cytokines such as IL6, IL1b, and TNF (cytokine storm) in the blood [[13], [14], [15], [16], [17], [18]] and its link with the outcome in COVID-19 patients

Chen, H., Battalapalli, D., Draz, M