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Under a balanced antioxidative state, NRF2 supports controlled NSCs-to-glial differentiation in wild-type mice, whereas in an oxidized redox environment it leads to premature depletion of the stem cell pool, as observed in NRF2 / mice (Robledinos-Anton et al., 2017)

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The extracted intracellular bacteria were plated on Middlebrook 7H10 agar plates (BD Difco)

While methylation plays a role in many central processes, its most important functions are: Controlling DNA/epigenetics Methylation is utilised in the body to switch genes off and on