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Both RSnH and H 2 S are generated through the nucleophilic substitution of sulfur atoms in organic polysulfides

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Lumigan (bimatoprost ophthalmic solution) is an FDA-approved medication widely prescribed to lower IOP in glaucoma patients

Upon cell incubation, the cell extracts are analyzed by MS techniques and metabolomic data is retrieved, metabolites annotated and metabolomic patterns associated to each specific mechanism of drug-induced toxicity are identified