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These ulcers exemplify the combined effect of oxidative stress and chronic inflammation, where inflammation and ROS together create a feedback loop that exacerbates immune dysfunction and worsens neuropathy, complicating patient care [42,46]

Downregulation of PHLDA1 can promote cancer cell proliferation and migration, resulting in poor prognosis 35

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9 Daily juicing of fruits and vegetables (organic is best)

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