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Conflicts of interest: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Psychosocial stress Psychosocial factors such as chronic stress, depression, and social isolation exert bidirectional regulatory effects on physiological aging processes through the brainperipheral organ axis, becoming a critical upstream risk factor for cognitive frailty

It also supports the skin's natural wound-healing processes and acts as an antioxidant, helping to protect against environmental stressors and free radical damage

doi: 10.3389/fnins.2012.00033 10

Some patients explore peptide therapy for wellness goals related to recovery, energy, and healthy aging support