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doi: 10.1038/s41392-021-00818-7 54 Raonyde FigueiredoCSPandolfoPGiestal-de-AraujoEOliveira-Silva BomfimPSavinoW

The light energy is absorbed by the melanin in the freckles, heating and destroying the pigment

First-Line Chemotherapy for Malignant Peripheral Nerve Sheath Tumor (MPNST) versus Other Histological Soft Tissue Sarcoma Subtypes and as a Prognostic Factor for MPNST: An EORTC Soft Tissue and Bone Sarcoma Group Study

For WADA to explicitly name these compounds in the 2026 list indicates they're aware of emerging use patterns

The short answer is yes
