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The replacement of Ala8 with Aib did not significantly change the binding affinity, but did result in a decline in potency as a substrate for DPP4
Thiffault, C., Aumont, N., Quirion, R
the Fate of Foreign Compounds in Biological Systems, 48 (4), 325331
However, this use is generally considered off-label in the United States (Garakani et al, 2020
Refer to the supplied COA or the COA policy for current documentation scope
