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This is supported in a study by Brignardello et al [214] that looked at gut permeability in asymptomatic, non-smoking obese volunteers and observed no differences compared to healthy controls

A meta-analysis of randomized controlled trials showed that use of antibiotics for acute rhinosinusitis offers a small therapeutic benefit over placebo, with a corresponding rise in the risk for adverse events.5 Reactive Oxygen Species (ROS) are produced under physiological conditions and their production and antioxidant activity are balanced

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