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Contribution of PIF4s DBD to its role in thermosensory gene expression Most DBDs, including the basic motif in bHLH, carry a net positive charge under physiological conditions, allowing their basic side chains to contact the acidic sugar-phosphate backbone of DNA nonspecifically 81
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Published studies in LC and ME/CFS have shown redox abnormalities in circulating components 75 , including serum proteins 59 and erthryocytes 60
