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In the present study, increased p62 transcriptional levels observed in untreated azoospermia may indicate disrupted autophagy, possibly due to impaired lysosomal degradation, resulting in cellular waste accumulation and increased germ cell loss 43,44,45
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Randomized proof of concept trial of GLYX-13, an N -methyl-D-aspartate receptor glycine site partial agonist, in major depressive disorder nonresponsive to a previous antidepressant agent
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10.1038/s41467-019-11682-z 113
