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A single dose of CJC-1295 increased GH secretion by 2 to 10-fold and IGF-1 levels by 1.5 to 3-fold for up to six days (Teichman, Journal of Clinical Endocrinology & Metabolism )
Following acclimation for seven days, mice were single-housed and maintained on HFD for 4 additional weeks
In addition, FcR-dependent activation of dendritic cells by agonistic ant-CD40 antibody was decreased by the persistence of IC in these mice
Consistently, miR-139-5p was shown to be able to suppress the formation of tumor metastasis in nude mice (89)
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