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5.4 Associated effects of atherosclerosis comorbidities on neutrophil metabolism Neutrophils exhibit metabolic reprogramming during metabolic disorders such as obesity and T2DM as important comorbidities and risk factors of atherosclerosis and CVD

Secondary antioxidants serve as scavengers for ROS

Additionally, propofol demonstrates an inhibitory effect on the expression of transglutaminase 2 (TGM2) in BV2 cells and microglia, leading to the suppression of NF-B signaling and microglia activation [78]
Radical reaction of oxygen with PUFAs has been extensively reviewed by Gardner in 1989, 299 and the nature and formation mechanisms of nonenzymatic LA metabolites has been reviewed by Spiteller in 1998