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Synergistic benefits have been observed with the coadministration of TQ and tacrolimus

Accumulation of zinc in intracellular milieu has been found to be associated with the death of dopaminergic neurons whereas chelation of zinc reverses the effect (Tamano et al., 2019)

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This may reflect specific compensatory metabolic rearrangement or changes in protein metabolism in the early stage of smoking or in the models, but results between animal and human cohorts are not always consistent (93)

doi: 10.3390/ijms22189990 90 IsraelyanN.Del ColleA.LiZ.ParkY.XingA.JacobsenJ