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This multidimensional heterogeneity collectively determines the therapeutic response to ferroptosis intervention and represents a key barrier in advancing current research toward precision-targeted strategies

Tumors were harvested at day 14 for scRNA-seq (Fig

Luminal solutes and ions can pass across the IEB via two main routes: the transcellular pathway or the paracellular pathway

On the basis of the complicated pathogenic mechanisms and unsatisfactory therapeutic outcome of DKD, determining the exact pathogenesis and developing appropriate treatment methods are quite necessary