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Description

The xCT/GSH/GPX4 pathway is an important component for ferroptosis (60)

Analysis of the redox metabolites from a single blood sample has been a challenge because of the different pH stability requirements of their reduced and oxidized forms, and the high protein concentration of the blood

Sample sources include: Fresh and frozen whole blood or buffy coat Plasma or serum Bone marrow Lymphocytes Platelets Body fluids Cultured cells Swabs and buccal cells Supporting data and figures Exemplary size distribution using QIAamp DNA Blood Mini Kit (Blood) Exemplary size distribution of DNA from blood using the QIAamp DNA Blood Mini Kit

Abstract Lactic acidosis is a feature of solid tumors and plays fundamental role(s) rendering cancer cells to adapt to diverse metabolic stresses, but the mechanism underlying its roles in redox homeostasis remains elusive