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, paracetamol preferentially inhibited brain cyclooxygenases (32)), thereby generalized convulsions, particularly presenting brain tissue's high susceptibility to oxidative stress, leaving the glutathione in the brain defenseless to depletion by paracetamol (4, 5), unless BPC 157 was applied

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68 Iron and iron derivatives, such as heme or [Fe-S] clusters, are the essential active centers of many enzymes that are involved in ROS generation (Lipoxygenases, cytochrome P450, NADPH oxidases et al.)

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