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2012;26 Suppl 1:108-117

Lowered response threshold and increased responsiveness to mechanical stimulation of cutaneous nociceptive fibers in streptozotocin-diabetic rat skin in vitro correlates of mechanical allodynia and hyperalgesia observed in the early stage of diabetes

The related mechanisms mainly include excessive accumulation of ROS, excessive release of cortisol, decreased level of triiodothyronine, and misalignment of activin/statin/follistatin axis (Jiang et al

Considering the use of dialysis, annual mortality rates continue to be above 20%, with cardiovascular disease accounting for more than half of all fatalities [17]

When given together, dopamine and GHRH have additive effects on GH secretion, and similarly the dopamine agonist bromocriptine augments the effects of GHRH (402)
