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27 This is a double-blind placebo-controlled study testing the safety and efficacy of ALC compared to placebo in the treatment of pain in HIV-positive patients with distal symmetric polyneuropathy related to antiretroviral drugs

In addition, the low transdermal absorption rate and individual metabolic differences may affect the outcome, and it is necessary to combine scientific lifestyle intervention

Induction of mGlu2 receptors is mediated by acetylation mechanisms that involve transcription factors of the nuclear factor (NF)-B family.

People in the last stage of long-term, serious kidney disease need to undergo hemodialysis, which can lower L-carnitine levels

40 Sympathetic dominance (ie, excessive fight-or-flight activation relative to resting nervous system activity) and the inability to mount a normal adaptive response to stress promote multiple symptoms, including pain, cognitive dysfunction, and feelings of stress
