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Eventually, that weaker runner gets hurt, and the pair can't compete anymore

Haley N, Fowler SD, deDuve C

As evidence supporting metabolic disturbances in the process of developing MA use disorder, our previous study uncovered immediate and distinct changes in the metabolic pathways involved in energy metabolism, the nervous system, and membrane lipid metabolism in the plasma of MA self-administering rats during 24 h of short-term abstinence 13

Certain odors selectively activate and/or inhibit a single olfactory neuron, while some odors can stimulate a subset of neurons