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Several hallmarks of dysfunctional adipocytes were described to depend on transcriptionally regulated mechanisms, such as apoptosis, senescence, or altered adipokine and lipokine secretion 3

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Enhanced suicidal death of erythrocytes from gene-targeted mice lacking the Cl-/HCO(3)(-) exchanger AE1

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It can also have implications for treatment in healthcare settings where professionals have insufficient information about a treatment that customers may have received elsewhere