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The residues of the key 6 YGS 8 motif within the GCT fold are located in loop 1, while the unique dimerization loop 2 is flipped away from the enzymes core domain (Nguyen et al., 2020)

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Western blots The total amounts of hippocampal proteins (20 g) from three mice of each group were separated by 10% sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and transferred onto polyvinylidene difluoride (PVDF) membranes (cat# IPVH00010, Merck millipore, USA)

10.1016/j.sjbs.2021.05.044 156 PriscillaD

These reversible reactions are catalysed by a series of enzymes, including ribulose-5-phosphate epimerase, ribose-5-phosphate isomerase, transaldolase (TALDO) and the thiamine-dependent enzyme transketolase (TK