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General measures Options for symptomatic treatment include: [3] Pain management, e.g., acetaminophen , morphine Antiemetics, e.g., ondansetron Anxiolytics, e.g., lorazepam Beta blockers for hypertension and symptomatic tachycardia, e.g., propranolol ) Seizure management Ensure seizure precautions (especially if the patient has hyponatremia)

Persistent antigen at vaccination sites induces tumor-specific CD8(+) T cell sequestration, dysfunction and deletion

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Lam, Fui-Ching et al