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However, while downregulation of homeostatic functions and overrepresentation of immune-related pathways was initiated in control astrocytes after TBI, even without any injury, IKK2-CA GFAP astrocytes already showed an aggravation of these features due to NF-B activation per se, an effect which was further boosted by TBI

We increased the cellular levels of GSH by using exogenous GSH and OTC treatments that resulted in elevated levels of SA in leaves of wild type Xanthi NN and SA-deficient NahG tobacco plants

Such split is susceptible to clustering in chemical space, and therefore can result in structurally similar pesticides in both training and testing sets 20,46