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Otherwise I would have given a higher score
Simmonds P, Smith F, McOmish P, Yap J, Kolberg M, et al
Nat Commun 9 , 1967 (2018)
While PEGylation improves systemic circulation by reducing clearance, it does not inherently facilitate BBB penetration and may even hinder interaction with the endothelial surface
V.Gomez-CasatiD
