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Metastasis, the spread of cancer cells from the primary tumor to distant sites, is a hallmark of cancer and a major cause of cancer-related mortality [117]
A well-designed study should be built to detect them, not assume them away.
3.2 Meta-analysis results There were 34,814 participants (15,569 cases and 19,245 controls) in the 96 studies included in the meta-analysis
