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From amino acid metabolismsuch as arginine and tryptophanto sphingolipid and one-carbon metabolism, and further to the fine-tuning of mitochondrial dynamics and respiratory chain function, the metabolic network profoundly determines macrophage polarization fate and functional output by influencing epigenetic states, inflammasome activation, cytokine expression, and immune checkpoint signaling

Macedonian J Med Sci 7:495499

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MCE), BAY61-3606+luteolin 25 M, or an equal volume of DMSO at 37C for 10 min