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However, research shows that people with low B12 tend to have higher BMI, reduced physical activity, disrupted fat cell gene expression, and elevated homocysteine, all of which can contribute to gradual weight gain over time

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ACKNOWLEDGMENTS All authors participated in drafting, review and editing, of the manuscript and in the review and approval of the final version of the manuscript

The study used databases at the Toronto-based Institute for Clinical Evaluative Sciences to review the patient records of 146,850 residents of the province aged 65 or over who were prescribed regular vitamin B12 shot between January 2011 and October 2015