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Indeed, protective factors such as breastfeeding also emerged in some studies 195,300,303,304

doi: 10.1371/journal.pbio.1002533

Traditional Chinese medicine (TCM), with its inherent multi-target approach, aligns well with the multi-factorial pathogenesis of PD, which involves interconnected mechanisms such as oxidative stress, neuroinflammation, and mitochondrial dysfunction

The presence of LAB, that are prevalently saccharolytic, acidogenic and bacteriocin producers, acts as a selective agent, protecting the gut environment from putrefactive and sulphate-reducing bacteria known to be involved in the production of gas, thiols, phenols, indole, histolesive proteases, and carcinogens (Holzapfel et al., 1998)

Therefore, circ_0082374 depletion reduces NSCLC proliferation and the EMT process by decreasing GPX4 expression [99]