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The treatment period lasted 4-7 weeks before significant effects were observed

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To explore gene expression changes, a multivariate reanalysis of the GSE1073233 dataset was performed, revealing major differences between untreated HepG2 and HepG2 ATP7B-KO cells, particularly in autophagy, lipid metabolism, and stress-related pathways

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J Pediatr 139:2733 Warner BW, Ziegler MM (1993) Management of the short bowel syndrome in the pediatric population