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Zhang et al., 2017a)

What darkens your skin and eyes is melanin

Research on MOTS-c in ovariectomized mice (a model for postmenopausal metabolic dysfunction) showed reduced fat accumulation in white adipose tissue, increased brown fat activation, and improved insulin sensitivity after just 5 weeks of treatment

The effect of oral ferrous sulfate use in different posology on laboratory values and clinical findings related to iron metabolism in anemia due to iron deficiency

In the case of utilizing experimental models similar to humans in preclinical research, the failure of clinical translation not only indicates that we need to find a preclinical model that is more suitable for humans but also motivates us to look for multi-target and multi-pathway neuroprotective drugs
