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Prodrug development has also advanced EGCGs pharmacokinetic properties by creating EGCG prodrugs through strategic chemical modifications

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Neurology 82 (18), 16139

Impact of lifestyle and socioeconomic position on the association between non-steroidal anti-inflammatory drug use and major adverse cardiovascular events: a case-crossover study

However, transport of bilirubin across the hepatocyte, and indeed its initial uptake from the bloodstream, is relatively inefficient, so some conjugated and unconjugated bilirubin is present in plasma even under normal conditions
