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[DOI] [PubMed] [Google Scholar] Cantin AM, North SL, Hubbard RC, Crystal RG

PLoS One 7 , e51929, (2012)

Critically, exhausted T cells exhibit impaired metabolic fitness with significant reduced oxidative phosphorylation and glycolytic capacity, which has been reported to correlate with poor responses to ICIs in NSCLC and melanoma