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For the conversion of RNA to cDNA, cDNA synthesis with reverse transcriptase enzyme was performed using High-Capacity cDNA Reverse Transcription kit (4,368,814, Applied Biosystems, Foster City, California, USA)

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Elacestrant is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ER and ER, respectively

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Hepatic Detoxification It is primarily responsible for neutralizing toxins in the liver