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These receptor proteins are characterized by the presence of LIR motifs for the interaction with ATG8 family proteins such as LC3 on the surface of phagophores, and many have ubiquitin-binding domains capable of recognizing ubiquitinated cargo, thus establishing a bridge between the cargo and the autophagic machinery (40, 92, 93)

We recommend a cyclic therapy with 6 to 8-week cycles

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Huang et al., 2015) as a particular point, will be illustrated with the subsequent successful healing of the various fistulas (thereby, the simultaneous healing of the different tissues) (Klicek et al., 2008