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PMID 23356267

Finally, we demonstrate that TFG mutations linked to HSP cause profound defects in ESCRT recruitment and lysosomal membrane resealing

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Vitamin C can support folate retention, but only up to a point when EGCG concentrations exceed vitamin C levels, the protection is insufficient [4]. The Folic Acid Compounding Problem: A Double Hit to Natural Folate Metabolism Here is where the picture becomes even more important to understand and where conventional advice may be leading vulnerable people astray
