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Oxidative stress reduction: BPC-157s Nrf2 pathway activation in peripheral tissues (established in hepatocyte and endothelial cell research) may extend to CNS cells following TBI, upregulating glutathione synthesis, superoxide dismutase, and heme oxygenase-1 in neurons and astrocytes

In the clinical trials of treatment of GC with apatinib combined with docetaxel, the mPFS and mOS of the apatinib group and the combination group were 2.5 and 4 months, 3.3 and 6 months, respectively, and grade 3/4 adverse reactions such as neutrophils, cytopenia, anemia, thrombocytopenia, and hypertension were milder in the combination group than in the apatinib group (128)

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