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Professional medical supervision required for administration and monitoring
Med Chem Res 32 , 19721994 (2023)

The efficacy of setmelanotide may not be sufficient for POMC-MC4R deficient patients because body weight reduction ratio of semaglutide and tirzepatide were 12.4 and 17.8%, respectively in clinical study as compared with that of setmelanotide, 5.2% [[18, 19, 23]]

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It is used as a diluent to reconstitute or dilute injectable medications, allowing multi-dose use thanks to its preservative
