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(F) Histone lactylation inhibits RARg expression in macrophages, consequently enhancing IL-6 levels in the TME and endowing macrophages with tumor-promoting functions ( 4.4 Mammalian cell reprogramming Histone lactylation has also emerged as a crucial epigenetic factor in cellular reprogramming, directly linking metabolic shifts to gene expression regulation

Experimental Biology and Medicine 235: 2331

GHK-Cu is a biological repair signal , not a filler or neuromodulator
