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Dysfunction of GCs is a key factor in the development of POF (Wu et al., 2023)
If mitochondria are damaged, they slow down and make less energy
The primary limitation is the gap between preclinical and human data
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In addition to well-established transcriptomic and proteomic studies, other types of large-scale omics investigations are gaining momentum in IVD research as technologies become further refined, particularly in important mouse model studies (Veras et al., 2020)
