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doi: 10.21037/jtd-20-1555 52 MirzoevaSFranzenCAPellingJC

FDA granted it GRAS (Generally Recognized As Safe) status in 2014 as a food ingredient

Integrative control of gastrointestinal motility by nitric oxide

Injection site reactions affect roughly 3.2% of tirzepatide users in clinical trials, compared to just 0.4% on placebo

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